| 8. Jornada | 13.08.2022 | Club Tijuana [Sub 20] | - | Puebla FC [Sub 20] | 3:4 | ||||
| 10. Jornada | 20.08.2022 | Atlas Guadalajara [Sub 20] | - | Puebla FC [Sub 20] | 4:0 | ||||
| 11. Jornada | 26.08.2022 | Puebla FC [Sub 20] | - | FC Juárez [Sub 20] | 2:1 | ||||
| 12. Jornada | 01.09.2022 | Gallos Blancos [Sub 20] | - | Puebla FC [Sub 20] | 0:2 | ||||
| 13. Jornada | 07.09.2022 | Puebla FC [Sub 20] | - | CF Pachuca [Sub 20] | 1:2 | ||||
| 14. Jornada | 10.09.2022 | Deportivo Guadalajara [Sub 20] | - | Puebla FC [Sub 20] | 1:1 | ||||
| 9. Jornada | 13.09.2022 | Puebla FC [Sub 20] | - | Club Necaxa [Sub 20] | 3:2 | ||||
| 15. Jornada | 16.09.2022 | Puebla FC [Sub 20] | - | UANL Tigres [Sub 20] | 1:1 | ||||
| 5. Jornada | 22.09.2022 | CF Monterrey [Sub 20] | - | Puebla FC [Sub 20] | 3:3 |  |
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| 17. Jornada | 30.09.2022 | Puebla FC [Sub 20] | - | CF América [Sub 20] | 1:1 |  |
México