| 16. Jornada | 10.12.2000 | Club Brugge KV | - | Lierse SK (old) | 1:0 | ||||
| 17. Jornada | 17.12.2000 | KRC Genk | - | Club Brugge KV | 0:1 | ||||
| 19. Jornada | 19.01.2001 | Club Brugge KV | - | Excelsior Mouscron | 2:2 |  |
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| 20. Jornada | 27.01.2001 | Sporting Lokeren | - | Club Brugge KV | 2:2 | ||||
| 21. Jornada | 04.02.2001 | Club Brugge KV | - | Standard Liège | 1:1 | ||||
| 22. Jornada | 09.02.2001 | RAA La Louviére | - | Club Brugge KV | 1:1 | ||||
| 25. Jornada | 10.03.2001 | KV Mechelen | - | Club Brugge KV | 1:1 | ||||
| 26. Jornada | 18.03.2001 | Club Brugge KV | - | K.S.C. Eendracht Aalst | 1:1 | ||||
| 27. Jornada | 31.03.2001 | Sint-Truidense VV | - | Club Brugge KV | 1:2 |  |
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| 28. Jornada | 07.04.2001 | Club Brugge KV | - | KVC Westerlo | 2:2 | |
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| 29. Jornada | 14.04.2001 | KSK Beveren | - | Club Brugge KV | 0:2 | |
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| 30. Jornada | 22.04.2001 | Club Brugge KV | - | RSC Charleroi | 1:0 | ||||
| 31. Jornada | 29.04.2001 | Royal Antwerp FC | - | Club Brugge KV | 0:1 | ||||
| 32. Jornada | 05.05.2001 | Club Brugge KV | - | RSC Anderlecht | 0:1 | ||||
| 33. Jornada | 12.05.2001 | Lierse SK (old) | - | Club Brugge KV | 0:2 | ||||
| 34. Jornada | 20.05.2001 | Club Brugge KV | - | KRC Genk | 6:0 |
Bélgica
