| 1. Jornada | 21.08.2021 | FK Drenica | - | KF Gjilani | 1:1 | ||||
| 2. Jornada | 30.08.2021 | KF Dukagjini | - | FK Drenica | 1:2 | ||||
| 5. Jornada | 19.09.2021 | FK Drenica | - | Drita Gjilan | 0:2 | ||||
| 6. Jornada | 25.09.2021 | KF Llapi | - | FK Drenica | 1:1 | ||||
| 7. Jornada | 29.09.2021 | FK Drenica | - | KF Malisheva | 1:0 | ||||
| 8. Jornada | 02.10.2021 | KF Ballkani | - | FK Drenica | 3:2 |  |
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| 9. Jornada | 15.10.2021 | FK Drenica | - | KF Feronikeli | 4:0 | ||||
| 10. Jornada | 20.10.2021 | KF Gjilani | - | FK Drenica | 2:1 | ||||
| 12. Jornada | 31.10.2021 | KF Prishtina | - | FK Drenica | 1:0 | ||||
| 14. Jornada | 20.11.2021 | Drita Gjilan | - | FK Drenica | 1:0 | ||||
| 15. Jornada | 25.11.2021 | FK Drenica | - | KF Llapi | 3:5 | ||||
| 16. Jornada | 28.11.2021 | KF Malisheva | - | FK Drenica | 2:0 | ||||
| 17. Jornada | 04.12.2021 | FK Drenica | - | KF Ballkani | 0:1 | ||||
| 18. Jornada | 11.12.2021 | KF Feronikeli | - | FK Drenica | 0:2 |
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