| 7. Jornada | 24.02.2022 | CF Pachuca [Sub 20] | - | Mazatlán FC [Sub 20] | 3:2 | ||||
| 15. Jornada | 19.04.2022 | Mazatlán FC [Sub 20] | - | Santos Laguna [Sub 20] | 1:2 | ||||
| 16. Jornada | 22.04.2022 | FC Juárez [Sub 20] | - | Mazatlán FC [Sub 20] | 3:0 |  |
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| 17. Jornada | 29.04.2022 | Mazatlán FC [Sub 20] | - | Puebla FC [Sub 20] | 4:1 |
México