| 2. Jornada | 16.01.2021 | Club Necaxa | - | Atlético San Luis | 1:0 | ||||
| 3. Jornada | 24.01.2021 | Deportivo Toluca | - | Club Necaxa | 2:0 | ||||
| 4. Jornada | 29.01.2021 | UANL Tigres | - | Club Necaxa | 1:1 |  |
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| 5. Jornada | 06.02.2021 | Club Necaxa | - | Cruz Azul | 0:2 | ||||
| 6. Jornada | 14.02.2021 | Deportivo Guadalajara | - | Club Necaxa | 2:2 | ||||
| 8. Jornada | 27.02.2021 | Puebla FC | - | Club Necaxa | 1:0 | ||||
| 13. Jornada | 04.04.2021 | CF América | - | Club Necaxa | 2:1 | ||||
| 17. Jornada | 01.05.2021 | Club Necaxa | - | Atlas Guadalajara | 1:5 |
México