| 7. Jornada | 15.08.2016 | Guaraní | - | Club Nacional | 1:0 |  |
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| 14. Jornada | 15.10.2016 | Sol de América | - | Club Nacional | 0:1 | ||||
| 15. Jornada | 24.10.2016 | Sportivo Luqueño | - | Club Nacional | 2:1 | ||||
| 17. Jornada | 07.11.2016 | General Díaz | - | Club Nacional | 0:2 |  |
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| 18. Jornada | 21.11.2016 | Club Nacional | - | Guaraní | 1:1 | ||||
| 19. Jornada | 27.11.2016 | Club Olimpia | - | Club Nacional | 2:1 | ||||
| 20. Jornada | 04.12.2016 | Club Nacional | - | Club Rubio Ñu | 3:1 | ||||
| 21. Jornada | 11.12.2016 | General Caballero ZC | - | Club Nacional | 1:2 | ||||
| 22. Jornada | 18.12.2016 | Club Nacional | - | River Plate | 2:0 |
Paraguay