| 1. Jornada | 19.09.2021 | UE Santa Coloma | - | FC Santa Coloma | 2:1 | ||||
| 2. Jornada | 26.09.2021 | FC Santa Coloma | - | UE Engordany | 1:1 | ||||
| 3. Jornada | 03.10.2021 | CE Carroi | - | FC Santa Coloma | 2:5 | ||||
| 4. Jornada | 17.10.2021 | FC Santa Coloma | - | FC Ordino | 3:2 | ||||
| 5. Jornada | 24.10.2021 | FC Santa Coloma | - | UE Sant Julià | 1:3 |  |
|||
| 9. Jornada | 28.11.2021 | UE Engordany | - | FC Santa Coloma | 2:4 | |
|||
| 12. Jornada | 19.01.2022 | UE Sant Julià | - | FC Santa Coloma | 0:0 | |
|||
| 8. Jornada | 26.01.2022 | FC Santa Coloma | - | UE Santa Coloma | 3:1 | ||||
| 13. Jornada | 30.01.2022 | FC Santa Coloma | - | Inter Club d'Escaldes | 3:2 | ||||
| 11. Jornada | 02.02.2022 | FC Ordino | - | FC Santa Coloma | 0:0 | ||||
| 14. Jornada | 06.02.2022 | Atlétic Escaldes | - | FC Santa Coloma | 2:1 | |
|||
| 15. Jornada | 13.02.2022 | UE Santa Coloma | - | FC Santa Coloma | 1:1 | ||||
| 16. Jornada | 20.02.2022 | FC Santa Coloma | - | UE Engordany | 1:1 | ||||
| 18. Jornada | 06.03.2022 | FC Santa Coloma | - | FC Ordino | 2:1 | |
|||
| 20. Jornada | 20.03.2022 | Inter Club d'Escaldes | - | FC Santa Coloma | 1:2 |
España