| 1. Jornada | 02.08.2003 | Club Necaxa | - | Real San Luis | 1:1 | ||||
| 2. Jornada | 09.08.2003 | Real San Luis | - | Puebla FC | 4:0 |  |
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| 3. Jornada | 17.08.2003 | Pumas UNAM | - | Real San Luis | 0:0 | ||||
| 4. Jornada | 23.08.2003 | Real San Luis | - | Cruz Azul | 0:0 | ||||
| 5. Jornada | 30.08.2003 | Veracruz (old) | - | Real San Luis | 3:1 |  |
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| 7. Jornada | 13.09.2003 | CF Monterrey | - | Real San Luis | 3:2 | ||||
| 8. Jornada | 20.09.2003 | Real San Luis | - | CF América | 1:5 | ||||
| 9. Jornada | 24.09.2003 | Atlas Guadalajara | - | Real San Luis | 4:1 | |
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| 10. Jornada | 27.09.2003 | Real San Luis | - | Club Irapuato | 0:0 | ||||
| 11. Jornada | 04.10.2003 | Real San Luis | - | Santos Laguna | 3:0 | ||||
| 12. Jornada | 12.10.2003 | Atlante | - | Real San Luis | 2:0 | ||||
| 13. Jornada | 18.10.2003 | Real San Luis | - | Jaguares Chiapas | 1:2 | |
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| 14. Jornada | 22.10.2003 | CF Pachuca | - | Real San Luis | 2:0 | ||||
| 15. Jornada | 25.10.2003 | Real San Luis | - | Monarcas Morelia | 0:1 | ||||
| 16. Jornada | 02.11.2003 | Gallos Blancos (old) | - | Real San Luis | 4:4 | |
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| 18. Jornada | 11.11.2003 | Deportivo Toluca | - | Real San Luis | 5:0 | ||||
| 19. Jornada | 22.11.2003 | Real San Luis | - | Deportivo Guadalajara | 1:2 |
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