| 3. Jornada | 03.02.2008 | Cruz Azul | - | Club San Luis | 4:0 | ||||
| 5. Jornada | 14.02.2008 | Veracruz (old) | - | Club San Luis | 1:1 | ||||
| 8. Jornada | 02.03.2008 | Club San Luis | - | Atlante | 2:0 |  |
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| 9. Jornada | 09.03.2008 | CF América | - | Club San Luis | 1:2 | ||||
| 10. Jornada | 16.03.2008 | Club San Luis | - | CF Monterrey | 3:1 |  |
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| 11. Jornada | 23.03.2008 | Puebla FC | - | Club San Luis | 1:2 | ||||
| 12. Jornada | 30.03.2008 | Club San Luis | - | Jaguares Chiapas | 0:2 | ||||
| 13. Jornada | 06.04.2008 | Pumas UNAM | - | Club San Luis | 2:3 | ||||
| 14. Jornada | 13.04.2008 | Club San Luis | - | UAG Tecos | 1:1 | ||||
| 15. Jornada | 20.04.2008 | Monarcas Morelia | - | Club San Luis | 1:2 | ||||
| 17. Jornada | 04.05.2008 | Santos Laguna | - | Club San Luis | 4:1 | |
México