| 1. Jornada | 04.07.2022 | Santos Laguna | - | CF Monterrey | 4:3 |  |
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| 2. Jornada | 10.07.2022 | CF Monterrey | - | CF América | 3:2 | |
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| 3. Jornada | 18.07.2022 | Atlético San Luis | - | CF Monterrey | 0:1 | ||||
| 7. Jornada | 07.08.2022 | CF Monterrey | - | Club León | 5:1 | ||||
| 8. Jornada | 13.08.2022 | Club Necaxa | - | CF Monterrey | 1:2 | |
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| 9. Jornada | 18.08.2022 | Deportivo Toluca | - | CF Monterrey | 1:1 | |
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| 10. Jornada | 21.08.2022 | CF Monterrey | - | UANL Tigres | 0:0 |  |
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| 16. Jornada | 24.08.2022 | Deportivo Guadalajara | - | CF Monterrey | 1:0 | ||||
| 11. Jornada | 29.08.2022 | Club Tijuana | - | CF Monterrey | 0:3 | |
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| 12. Jornada | 04.09.2022 | CF Monterrey | - | Mazatlán FC | 0:0 | ||||
| 13. Jornada | 07.09.2022 | CF Monterrey | - | Cruz Azul | 3:2 | ||||
| 14. Jornada | 10.09.2022 | FC Juárez | - | CF Monterrey | 0:1 | ||||
| 15. Jornada | 18.09.2022 | CF Monterrey | - | Atlas Guadalajara | 2:0 | ||||
| 17. Jornada | 02.10.2022 | CF Monterrey | - | CF Pachuca | 0:0 |
Uruguay
