| 1. Jornada | 08.01.2022 | Cruz Azul [Sub 18] | - | Club Tijuana [Sub 18] | 3:2 | ||||
| 2. Jornada | 15.01.2022 | Cruz Azul [Sub 18] | - | FC Juárez [Sub 18] | 1:0 | ||||
| 3. Jornada | 22.01.2022 | CF Monterrey [Sub 18] | - | Cruz Azul [Sub 18] | 1:0 | ||||
| 4. Jornada | 07.02.2022 | Club León [Sub 18] | - | Cruz Azul [Sub 18] | 1:0 | ||||
| 5. Jornada | 12.02.2022 | Cruz Azul [Sub 18] | - | Club Necaxa [Sub 18] | 2:1 |  |
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| 6. Jornada | 20.02.2022 | Deportivo Toluca [Sub 18] | - | Cruz Azul [Sub 18] | 1:1 |
México