| 3. Jornada | 22.01.2022 | CF Monterrey [Sub 20] | - | Cruz Azul [Sub 20] | 2:2 | ||||
| 5. Jornada | 12.02.2022 | Cruz Azul [Sub 20] | - | Club Necaxa [Sub 20] | 0:1 | ||||
| 6. Jornada | 20.02.2022 | Deportivo Toluca [Sub 20] | - | Cruz Azul [Sub 20] | 1:1 | ||||
| 7. Jornada | 27.02.2022 | Cruz Azul [Sub 20] | - | Santos Laguna [Sub 20] | 2:1 |  |
|||
| 8. Jornada | 02.03.2022 | UANL Tigres [Sub 20] | - | Cruz Azul [Sub 20] | 1:1 |
México