| 1. Jornada | 10.02.2022 | Arsenal de Sarandí II | - | Rosario Central II | 2:1 | ||||
| 2. Jornada | 15.02.2022 | Rosario Central II | - | Vélez Sarsfield II | 1:1 | ||||
| 4. Jornada | 26.02.2022 | Rosario Central II | - | Godoy Cruz II | 5:1 |  |
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| 5. Jornada | 04.03.2022 | Central Córdoba SdE II | - | Rosario Central II | 0:3 | |
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| 6. Jornada | 11.03.2022 | Rosario Central II | - | Barracas Central II | 1:2 | ||||
| 7. Jornada | 18.03.2022 | Rosario Central II | - | Newell's Old Boys II | 2:1 | ||||
| 8. Jornada | 01.04.2022 | Tigre II | - | Rosario Central II | 1:3 | ||||
| 11. Jornada | 19.04.2022 | Lanús II | - | Rosario Central II | 1:0 | ||||
| 12. Jornada | 25.04.2022 | Rosario Central II | - | Independiente II | 1:2 | ||||
| 13. Jornada | 29.04.2022 | Huracán II | - | Rosario Central II | 3:0 | ||||
| 14. Jornada | 05.05.2022 | Rosario Central II | - | Estudiantes II | 0:1 |
Paraguay