| 1. Jornada | 08.08.2010 | River Plate | - | Tigre | 1:0 |  |
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| 2. Jornada | 15.08.2010 | Huracán | - | River Plate | 0:1 | ||||
| 3. Jornada | 22.08.2010 | River Plate | - | Independiente | 3:2 | |
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| 4. Jornada | 29.08.2010 | Argentinos Juniors | - | River Plate | 0:0 | ||||
| 5. Jornada | 06.09.2010 | Vélez Sarsfield | - | River Plate | 2:1 | ||||
| 6. Jornada | 12.09.2010 | River Plate | - | Arsenal de Sarandí | 1:0 | |
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| 7. Jornada | 19.09.2010 | Newell's Old Boys | - | River Plate | 1:0 | ||||
| 8. Jornada | 27.09.2010 | River Plate | - | Quilmes | 1:1 | ||||
| 9. Jornada | 04.10.2010 | Banfield | - | River Plate | 2:2 | |
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| 10. Jornada | 11.10.2010 | River Plate | - | Gimnasia de La Plata | 0:0 | ||||
| 11. Jornada | 18.10.2010 | Godoy Cruz | - | River Plate | 2:2 | |
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| 12. Jornada | 23.10.2010 | River Plate | - | Racing Club | 1:1 | ||||
| 13. Jornada | 07.11.2010 | All Boys | - | River Plate | 1:0 | ||||
| 14. Jornada | 16.11.2010 | River Plate | - | Boca Juniors | 1:0 | ||||
| 15. Jornada | 21.11.2010 | San Lorenzo | - | River Plate | 0:0 | ||||
| 16. Jornada | 28.11.2010 | River Plate | - | Olimpo de Bahía Blanca | 1:0 | ||||
| 17. Jornada | 05.12.2010 | Colón de Santa Fe | - | River Plate | 1:2 | ||||
| 18. Jornada | 08.12.2010 | River Plate | - | Estudiantes | 0:4 | |
Argentina
Estados Unidos 
