| 7. Jornada | 07.03.2022 | Valledupar FC | - | Deportes Quindío | 0:0 | ||||
| 8. Jornada | 11.03.2022 | Boyacá Chicó | - | Valledupar FC | 2:2 | ||||
| 9. Jornada | 20.03.2022 | Valledupar FC | - | Boca Juniors de Cali | 2:1 | ||||
| 11. Jornada | 03.04.2022 | Tigres FC | - | Valledupar FC | 3:2 |  |
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| 12. Jornada | 10.04.2022 | Valledupar FC | - | Fortaleza FC | 1:1 | ||||
| 13. Jornada | 16.04.2022 | Barranquilla FC | - | Valledupar FC | 1:1 | ||||
| 14. Jornada | 24.04.2022 | Valledupar FC | - | Atlético Huila | 1:0 | ||||
| 15. Jornada | 04.05.2022 | Real Cartagena | - | Valledupar FC | 1:2 |
Colombia