| 9. Jornada | 24.03.2023 | Guaraní | - | Guaireña FC | 1:1 | ||||
| 10. Jornada | 01.04.2023 | Club Olimpia | - | Guaraní | 0:1 | ||||
| 11. Jornada | 11.04.2023 | Guaraní | - | General Caballero DJLM | 3:1 |  |
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| 12. Jornada | 14.04.2023 | Guaraní | - | Libertad | 0:0 | ||||
| 14. Jornada | 25.04.2023 | Guaraní | - | Cerro Porteño | 0:3 | ||||
| 15. Jornada | 29.04.2023 | Guaraní | - | Resistencia SC | 1:0 | ||||
| 16. Jornada | 06.05.2023 | Sportivo Luqueño | - | Guaraní | 3:0 | ||||
| 17. Jornada | 14.05.2023 | Guaraní | - | Club Nacional | 2:2 | ||||
| 18. Jornada | 18.05.2023 | Tacuary | - | Guaraní | 1:3 | ||||
| 20. Jornada | 29.05.2023 | Guaireña FC | - | Guaraní | 2:2 | ||||
| 21. Jornada | 03.06.2023 | Guaraní | - | Club Olimpia | 1:2 |  |
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| 22. Jornada | 10.06.2023 | General Caballero DJLM | - | Guaraní | 0:0 | |
Paraguay