| 1. Jornada | 22.01.2020 | Blooming | - | Real Santa Cruz | 1:1 | ||||
| 2. Jornada | 27.01.2020 | Real Santa Cruz | - | The Strongest | 3:2 | ||||
| 4. Jornada | 02.02.2020 | Real Potosí | - | Real Santa Cruz | 2:1 | ||||
| 5. Jornada | 09.02.2020 | Always Ready | - | Real Santa Cruz | 6:0 | ||||
| 8. Jornada | 22.02.2020 | Atlético Palmaflor | - | Real Santa Cruz | 2:1 |  |
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| 15. Jornada | 03.12.2020 | The Strongest | - | Real Santa Cruz | 4:2 | ||||
| 16. Jornada | 07.12.2020 | Club San José | - | Real Santa Cruz | 4:1 | ||||
| 17. Jornada | 09.12.2020 | Real Santa Cruz | - | Real Potosí | 3:1 | |
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| 18. Jornada | 12.12.2020 | Real Santa Cruz | - | Always Ready | 0:3 | ||||
| 21. Jornada | 19.12.2020 | Real Santa Cruz | - | Atlético Palmaflor | 2:1 | ||||
| 22. Jornada | 22.12.2020 | Bolívar | - | Real Santa Cruz | 4:0 | ||||
| 24. Jornada | 27.12.2020 | Nacional Potosí | - | Real Santa Cruz | 1:0 |
Bolivia