| 1. Jornada | 15.08.2021 | Excelsior Virton | - | KVC Westerlo | 0:2 |  |
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| 2. Jornada | 22.08.2021 | Lierse Kempenzonen | - | Excelsior Virton | 2:0 | ||||
| 3. Jornada | 27.08.2021 | RWD Molenbeek | - | Excelsior Virton | 0:0 | ||||
| 4. Jornada | 11.09.2021 | Excelsior Virton | - | Lommel SK | 2:1 | ||||
| 5. Jornada | 18.09.2021 | Royal Excel Mouscron | - | Excelsior Virton | 1:1 | |
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| 6. Jornada | 26.09.2021 | Excelsior Virton | - | SK Deinze | 1:1 | ||||
| 7. Jornada | 03.10.2021 | Waasland-Beveren | - | Excelsior Virton | 4:3 | ||||
| 8. Jornada | 16.10.2021 | Excelsior Virton | - | Lierse Kempenzonen | 2:1 | ||||
| 9. Jornada | 24.10.2021 | KVC Westerlo | - | Excelsior Virton | 2:0 | |
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| 10. Jornada | 29.10.2021 | Excelsior Virton | - | Royal Excel Mouscron | 0:2 | ||||
| 11. Jornada | 05.11.2021 | Lommel SK | - | Excelsior Virton | 1:3 | ||||
| 12. Jornada | 21.11.2021 | Excelsior Virton | - | RWD Molenbeek | 0:2 | ||||
| 13. Jornada | 26.11.2021 | Excelsior Virton | - | Waasland-Beveren | 0:3 | |
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| 14. Jornada | 03.12.2021 | SK Deinze | - | Excelsior Virton | 3:0 | ||||
| 15. Jornada | 12.12.2021 | Excelsior Virton | - | Lierse Kempenzonen | 2:2 |
Francia