| 2. Jornada | 24.07.2021 | Academica Clinceni | - | CFR Cluj | 1:2 | ||||
| 5. Jornada | 13.08.2021 | CFR Cluj | - | Farul Constanța | 1:0 | ||||
| 6. Jornada | 21.08.2021 | Argeș Pitești | - | CFR Cluj | 0:1 | ||||
| 7. Jornada | 29.08.2021 | CFR Cluj | - | FCSB | 4:1 |  |
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| 8. Jornada | 11.09.2021 | FC Botoşani | - | CFR Cluj | 1:0 | ||||
| 12. Jornada | 17.10.2021 | Rapid Bucureşti | - | CFR Cluj | 2:0 | ||||
| 16. Jornada | 20.11.2021 | FC Universitatea Craiova | - | CFR Cluj | 0:2 | |
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| 17. Jornada | 29.11.2021 | CFR Cluj | - | Academica Clinceni | 2:0 | |
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| 18. Jornada | 04.12.2021 | Chindia Târgoviște | - | CFR Cluj | 0:1 | ||||
| 19. Jornada | 12.12.2021 | CFR Cluj | - | CS Mioveni | 1:0 |
Islandia