| 10. Jornada | 16.10.2021 | East Fife FC | - | Cove Rangers | 4:2 | ||||
| 11. Jornada | 23.10.2021 | Montrose FC | - | East Fife FC | 4:1 | ||||
| 12. Jornada | 30.10.2021 | East Fife FC | - | Dumbarton FC | 2:1 | ||||
| 13. Jornada | 06.11.2021 | Queen's Park FC | - | East Fife FC | 1:1 |  |
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| 14. Jornada | 13.11.2021 | East Fife FC | - | Airdrieonians FC | 0:1 | |
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| 15. Jornada | 20.11.2021 | Clyde FC | - | East Fife FC | 3:1 | ||||
| 20. Jornada | 02.01.2022 | East Fife FC | - | Montrose FC | 0:2 | ||||
| 21. Jornada | 08.01.2022 | Airdrieonians FC | - | East Fife FC | 3:0 | |
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| 22. Jornada | 15.01.2022 | Dumbarton FC | - | East Fife FC | 2:0 | |
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| 18. Jornada | 22.01.2022 | East Fife FC | - | Falkirk FC | 0:2 | ||||
| 23. Jornada | 29.01.2022 | East Fife FC | - | Peterhead FC | 0:0 | |
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| 24. Jornada | 05.02.2022 | East Fife FC | - | Clyde FC | 0:0 | ||||
| 25. Jornada | 12.02.2022 | Alloa Athletic | - | East Fife FC | 1:3 |  |
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| 27. Jornada | 26.02.2022 | Falkirk FC | - | East Fife FC | 3:1 | |
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| 28. Jornada | 05.03.2022 | Montrose FC | - | East Fife FC | 0:0 | ||||
| 29. Jornada | 12.03.2022 | East Fife FC | - | Dumbarton FC | 2:0 |
Escocia