| 2. Jornada | 01.05.2021 | Phoenix Rising | - | San Diego Loyal | 4:1 | ||||
| 2. Jornada | 07.05.2021 | Rio Grande Valley FC | - | San Diego Loyal | 1:0 | ||||
| 2. Jornada | 14.05.2021 | Tacoma Defiance | - | San Diego Loyal | 3:1 | ||||
| 3. Jornada | 06.06.2021 | Phoenix Rising | - | San Diego Loyal | 2:2 | ||||
| 4. Jornada | 30.07.2021 | Tacoma Defiance | - | San Diego Loyal | 2:1 | ||||
| 5. Jornada | 02.08.2021 | Los Angeles Galaxy II | - | San Diego Loyal | 0:2 | ||||
| 5. Jornada | 08.08.2021 | San Diego Loyal | - | Real Monarchs SLC | 0:1 | ||||
| 6. Jornada | 23.09.2021 | Oakland Roots | - | San Diego Loyal | 2:1 | ||||
| 7. Jornada | 25.10.2021 | San Diego Loyal | - | Oakland Roots | 3:4 |
Estados Unidos
Italia