| 19. Jornada | 22.01.2022 | UD SS Reyes | - | Celta B | 0:7 | ||||
| 24. Jornada | 20.02.2022 | Zamora CF | - | UD SS Reyes | 0:3 | ||||
| 25. Jornada | 27.02.2022 | UD SS Reyes | - | Deportivo | 0:0 | ||||
| 26. Jornada | 05.03.2022 | SD Logroñés | - | UD SS Reyes | 1:0 | ||||
| 27. Jornada | 12.03.2022 | UD SS Reyes | - | CD Calahorra | 0:3 | ||||
| 28. Jornada | 19.03.2022 | Real Unión | - | UD SS Reyes | 0:1 | ||||
| 29. Jornada | 27.03.2022 | Racing de Ferrol | - | UD SS Reyes | 1:0 | ||||
| 30. Jornada | 01.04.2022 | UD SS Reyes | - | Real Racing | 0:1 |  |
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| 31. Jornada | 09.04.2022 | Celta B | - | UD SS Reyes | 1:2 | |
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| 32. Jornada | 17.04.2022 | UD SS Reyes | - | CyD Leonesa | 0:3 | ||||
| 33. Jornada | 24.04.2022 | Inter de Madrid | - | UD SS Reyes | 0:0 | ||||
| 34. Jornada | 01.05.2022 | UD SS Reyes | - | Valladolid B | 1:1 | ||||
| 35. Jornada | 08.05.2022 | Rayo Majadahonda | - | UD SS Reyes | 1:0 | ||||
| 36. Jornada | 13.05.2022 | UD SS Reyes | - | Unionistas CF | 1:2 | ||||
| 37. Jornada | 21.05.2022 | CD Tudelano | - | UD SS Reyes | 0:2 |  |
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| 38. Jornada | 27.05.2022 | UD SS Reyes | - | Bilbao Athletic | 2:0 |
España