| 6. Jornada | 28.08.2021 | Botev Vratsa | - | Lokomotiv Plovdiv | 0:0 | ||||
| 7. Jornada | 12.09.2021 | CSKA 1948 Sofia | - | Botev Vratsa | 5:1 | ||||
| 8. Jornada | 19.09.2021 | Botev Vratsa | - | CSKA Sofia | 2:4 | ||||
| 9. Jornada | 26.09.2021 | PFC Ludogorets Razgrad | - | Botev Vratsa | 3:1 | ||||
| 12. Jornada | 23.10.2021 | Botev Vratsa | - | Cherno More Varna | 0:0 | ||||
| 13. Jornada | 30.10.2021 | Slavia Sofia | - | Botev Vratsa | 1:0 | ||||
| 15. Jornada | 22.11.2021 | Levski Sofia | - | Botev Vratsa | 0:0 | ||||
| 17. Jornada | 30.11.2021 | Botev Plovdiv | - | Botev Vratsa | 2:1 | ||||
| 18. Jornada | 04.12.2021 | Botev Vratsa | - | PFC Beroe | 1:0 |  |
|||
| 19. Jornada | 10.12.2021 | Lokomotiv Plovdiv | - | Botev Vratsa | 2:4 | |
|||
| 20. Jornada | 19.02.2022 | Botev Vratsa | - | CSKA 1948 Sofia | 0:4 | ||||
| 21. Jornada | 25.02.2022 | CSKA Sofia | - | Botev Vratsa | 4:0 | ||||
| 22. Jornada | 07.03.2022 | Botev Vratsa | - | PFC Ludogorets Razgrad | 1:2 | ||||
| 24. Jornada | 20.03.2022 | Botev Vratsa | - | Pirin Blagoevgrad | 0:3 | ||||
| 26. Jornada | 08.04.2022 | Botev Vratsa | - | Slavia Sofia | 2:1 |
Bulgaria