| 11. Jornada | 31.10.2020 | Club Brugge KV | - | KV Mechelen | 2:2 | ||||
| 12. Jornada | 06.11.2020 | KV Mechelen | - | Sporting Charleroi | 3:3 |  |
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| 16. Jornada | 13.12.2020 | KV Mechelen | - | Waasland-Beveren | 2:3 | ||||
| 18. Jornada | 17.12.2020 | KV Mechelen | - | Club Brugge KV | 0:3 | ||||
| 25. Jornada | 20.01.2021 | KV Mechelen | - | Standard Liège | 0:4 | ||||
| 21. Jornada | 23.01.2021 | KV Mechelen | - | KAS Eupen | 3:0 | ||||
| 22. Jornada | 26.01.2021 | Waasland-Beveren | - | KV Mechelen | 2:3 | ||||
| 23. Jornada | 30.01.2021 | KV Mechelen | - | KRC Genk | 0:0 | ||||
| 27. Jornada | 19.02.2021 | KV Mechelen | - | Gante | 1:1 | ||||
| 28. Jornada | 27.02.2021 | KV Oostende | - | KV Mechelen | 2:0 | ||||
| 29. Jornada | 07.03.2021 | RSC Anderlecht | - | KV Mechelen | 1:1 | ||||
| 31. Jornada | 21.03.2021 | KV Mechelen | - | Oud-Heverlee Leuven | 2:2 | |
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| 32. Jornada | 03.04.2021 | Sint-Truidense VV | - | KV Mechelen | 2:1 | ||||
| 33. Jornada | 10.04.2021 | KV Mechelen | - | SV Zulte Waregem | 4:2 | ||||
| 34. Jornada | 18.04.2021 | KV Kortrijk | - | KV Mechelen | 1:4 | |
Bélgica
