| 22. Jornada | 31.01.2021 | SC Cambuur | - | MVV | 2:0 | ||||
| 23. Jornada | 06.02.2021 | MVV | - | NEC Nijmegen | 2:1 | ||||
| 24. Jornada | 13.02.2021 | De Graafschap | - | MVV | 1:0 | ||||
| 25. Jornada | 20.02.2021 | MVV | - | SBV Excelsior | 1:0 | ||||
| 26. Jornada | 26.02.2021 | MVV | - | Telstar | 2:0 | ||||
| 27. Jornada | 05.03.2021 | FC Utrecht (J) | - | MVV | 0:1 | ||||
| 28. Jornada | 12.03.2021 | MVV | - | AZ Alkmaar (J) | 3:2 | ||||
| 29. Jornada | 19.03.2021 | Jong Ajax | - | MVV | 4:3 | ||||
| 30. Jornada | 26.03.2021 | MVV | - | Almere City FC | 2:0 |  |
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| 31. Jornada | 02.04.2021 | MVV | - | FC Eindhoven | 2:0 | ||||
| 32. Jornada | 05.04.2021 | Jong PSV | - | MVV | 3:1 | ||||
| 33. Jornada | 12.04.2021 | MVV | - | Roda JC Kerkrade | 2:4 |  |
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| 34. Jornada | 16.04.2021 | TOP Oss | - | MVV | 2:2 | ||||
| 35. Jornada | 23.04.2021 | FC Dordrecht | - | MVV | 0:1 | |
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| 36. Jornada | 30.04.2021 | MVV | - | FC Volendam | 2:2 | |
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| 37. Jornada | 07.05.2021 | NAC Breda | - | MVV | 2:0 | ||||
| 38. Jornada | 12.05.2021 | MVV | - | FC Den Bosch | 3:1 | |
Países Bajos