| 1. Jornada | 29.01.2012 | Club San José | - | Universitario de Sucre | 1:1 |  |
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| 2. Jornada | 01.02.2012 | La Paz FC | - | Club San José | 1:3 | |
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| 3. Jornada | 05.02.2012 | Club San José | - | Real Potosí | 1:0 |  |
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| 4. Jornada | 10.02.2012 | Club Aurora | - | Club San José | 1:1 | ||||
| 5. Jornada | 14.02.2012 | Blooming | - | Club San José | 2:0 |  |
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| 8. Jornada | 08.03.2012 | Club San José | - | Real Mamoré | 3:0 | ||||
| 9. Jornada | 11.03.2012 | Nacional Potosí | - | Club San José | 1:4 | ||||
| 10. Jornada | 18.03.2012 | Club San José | - | Oriente Petrolero | 2:2 | ||||
| 11. Jornada | 24.03.2012 | The Strongest | - | Club San José | 2:2 | ||||
| 12. Jornada | 29.03.2012 | Universitario de Sucre | - | Club San José | 2:2 | |
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| 13. Jornada | 31.03.2012 | Club San José | - | La Paz FC | 2:1 | ||||
| 14. Jornada | 08.04.2012 | Real Potosí | - | Club San José | 2:1 | |
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| 16. Jornada | 15.04.2012 | Club San José | - | Blooming | 2:0 | ||||
| 17. Jornada | 22.04.2012 | Club San José | - | Bolívar | 3:0 | |
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| 18. Jornada | 29.04.2012 | CD Guabirá | - | Club San José | 2:3 | |
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| 20. Jornada | 06.05.2012 | Club San José | - | Nacional Potosí | 3:0 | ||||
| 21. Jornada | 10.05.2012 | Oriente Petrolero | - | Club San José | 2:1 | |
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Argentina