| 1. Jornada | 10.07.2010 | Shakhtar Donetsk | - | FK Krivbas (old) | 2:0 |  |
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| 2. Jornada | 18.07.2010 | Metalurg Zaporizhya | - | Shakhtar Donetsk | 1:1 | ||||
| 4. Jornada | 30.07.2010 | Arsenal Kiev | - | Shakhtar Donetsk | 1:3 | ||||
| 5. Jornada | 07.08.2010 | Shakhtar Donetsk | - | PFK Sevastopol | 5:0 | ||||
| 7. Jornada | 21.08.2010 | Volyn Lutsk | - | Shakhtar Donetsk | 0:1 | ||||
| 9. Jornada | 10.09.2010 | FK Obolon | - | Shakhtar Donetsk | 1:0 | ||||
| 11. Jornada | 25.09.2010 | Metalist Kharkiv | - | Shakhtar Donetsk | 1:2 | ||||
| 13. Jornada | 15.10.2010 | Metalurh Donetsk | - | Shakhtar Donetsk | 0:2 | ||||
| 18. Jornada | 20.11.2010 | Zorya Lugansk | - | Shakhtar Donetsk | 1:3 | ||||
| 19. Jornada | 28.11.2010 | Shakhtar Donetsk | - | Arsenal Kiev | 4:0 | ||||
| 22. Jornada | 20.03.2011 | Shakhtar Donetsk | - | Volyn Lutsk | 4:0 | ||||
| 26. Jornada | 23.04.2011 | Shakhtar Donetsk | - | Metalist Kharkiv | 2:1 | ||||
| 28. Jornada | 07.05.2011 | Shakhtar Donetsk | - | Metalurh Donetsk | 2:0 | |
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| 30. Jornada | 21.05.2011 | Shakhtar Donetsk | - | Dnipro Dnipropetrovsk | 0:0 |
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