| 2. Jornada | 13.05.2021 | Toronto FC | - | Columbus Crew | 2:0 | ||||
| 2. Jornada | 15.05.2021 | New York City FC | - | Toronto FC | 1:1 | ||||
| 3. Jornada | 24.06.2021 | Nashville SC | - | Toronto FC | 3:2 | ||||
| 3. Jornada | 27.06.2021 | Toronto FC | - | FC Cincinnati | 0:2 | ||||
| 4. Jornada | 08.07.2021 | New England Revolution | - | Toronto FC | 2:3 |  |
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| 4. Jornada | 18.07.2021 | Toronto FC | - | Orlando City | 1:1 | ||||
| 4. Jornada | 22.07.2021 | Toronto FC | - | New York RB | 1:1 | ||||
| 4. Jornada | 25.07.2021 | Chicago Fire | - | Toronto FC | 1:2 | ||||
| 5. Jornada | 28.08.2021 | CF Montréal | - | Toronto FC | 3:1 | ||||
| 6. Jornada | 12.09.2021 | FC Cincinnati | - | Toronto FC | 2:0 | ||||
| 6. Jornada | 15.09.2021 | Toronto FC | - | Inter Miami CF | 0:1 |
Japón