| 5. Jornada | 26.07.2022 | Club León [Sub 18] | - | Deportivo Toluca [Sub 18] | 2:2 |  |
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| 6. Jornada | 29.07.2022 | FC Juárez [Sub 18] | - | Deportivo Toluca [Sub 18] | 2:2 | |
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| 7. Jornada | 07.08.2022 | Deportivo Toluca [Sub 18] | - | Club Tijuana [Sub 18] | 2:1 | |
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| 8. Jornada | 14.08.2022 | Cruz Azul [Sub 18] | - | Deportivo Toluca [Sub 18] | 1:1 | ||||
| 9. Jornada | 17.08.2022 | Deportivo Toluca [Sub 18] | - | CF Monterrey [Sub 18] | 2:1 | |
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| 10. Jornada | 21.08.2022 | Atlético San Luis [Sub 18] | - | Deportivo Toluca [Sub 18] | 0:3 | |
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| 11. Jornada | 28.08.2022 | Deportivo Toluca [Sub 18] | - | CF Pachuca [Sub 18] | 3:1 | |
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| 12. Jornada | 04.09.2022 | Deportivo Toluca [Sub 18] | - | Deportivo Guadalajara [Sub 18] | 1:0 | |
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| 13. Jornada | 07.09.2022 | UANL Tigres [Sub 18] | - | Deportivo Toluca [Sub 18] | 3:2 | ||||
| 14. Jornada | 10.09.2022 | Deportivo Toluca [Sub 18] | - | Pumas UNAM [Sub 18] | 0:1 | ||||
| 15. Jornada | 16.09.2022 | Mazatlán FC [Sub 18] | - | Deportivo Toluca [Sub 18] | 4:1 | ||||
| 4. Jornada | 22.09.2022 | Deportivo Toluca [Sub 18] | - | Santos Laguna [Sub 18] | 4:0 | ||||
| 17. Jornada | 02.10.2022 | Deportivo Toluca [Sub 18] | - | Gallos Blancos [Sub 18] | 1:0 |
México