| 1. Jornada | 24.07.2021 | CF Monterrey [Sub 20] | - | Puebla FC [Sub 20] | 4:1 |  |
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| 2. Jornada | 31.07.2021 | CF Monterrey [Sub 20] | - | Pumas UNAM [Sub 20] | 3:1 | |
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| 3. Jornada | 06.08.2021 | Mazatlán FC [Sub 20] | - | CF Monterrey [Sub 20] | 1:4 | |
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| 4. Jornada | 14.08.2021 | CF Monterrey [Sub 20] | - | CF Pachuca [Sub 20] | 1:1 | |
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| 6. Jornada | 21.08.2021 | CF Monterrey [Sub 20] | - | Deportivo Guadalajara [Sub 20] | 1:1 | |
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| 8. Jornada | 11.09.2021 | Atlas Guadalajara [Sub 20] | - | CF Monterrey [Sub 20] | 3:1 | ||||
| 9. Jornada | 19.09.2021 | CF Monterrey [Sub 20] | - | UANL Tigres [Sub 20] | 0:1 | ||||
| 11. Jornada | 22.09.2021 | CF Monterrey [Sub 20] | - | Deportivo Toluca [Sub 20] | 1:0 | ||||
| 10. Jornada | 26.09.2021 | Santos Laguna [Sub 20] | - | CF Monterrey [Sub 20] | 4:1 | |
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| 14. Jornada | 19.10.2021 | Gallos Blancos [Sub 20] | - | CF Monterrey [Sub 20] | 1:1 | ||||
| 15. Jornada | 23.10.2021 | CF Monterrey [Sub 20] | - | Club Necaxa [Sub 20] | 5:1 | ||||
| 16. Jornada | 31.10.2021 | Atlético San Luis [Sub 20] | - | CF Monterrey [Sub 20] | 3:1 | |
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| 17. Jornada | 06.11.2021 | CF América [Sub 20] | - | CF Monterrey [Sub 20] | 2:0 |
México