| 3. Jornada | 05.02.2016 | Cerro Porteño | - | General Caballero ZC | 3:0 |  |
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| 4. Jornada | 08.02.2016 | Guaraní | - | Cerro Porteño | 0:0 | ||||
| 5. Jornada | 13.02.2016 | Cerro Porteño | - | Club Rubio Ñu | 1:2 | ||||
| 6. Jornada | 21.02.2016 | Club Olimpia | - | Cerro Porteño | 0:1 | |
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| 8. Jornada | 03.03.2016 | Libertad | - | Cerro Porteño | 2:1 | |
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| 9. Jornada | 06.03.2016 | Cerro Porteño | - | Club Nacional | 1:2 | ||||
| 11. Jornada | 21.03.2016 | Cerro Porteño | - | General Díaz | 2:2 | ||||
| 13. Jornada | 05.04.2016 | Cerro Porteño | - | Sportivo Luqueño | 2:1 | |
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| 16. Jornada | 12.05.2016 | Club Rubio Ñu | - | Cerro Porteño | 1:0 |
Paraguay