| 6. Jornada | 12.02.2022 | Club Necaxa [Sub 16] | - | CF Pachuca [Sub 16] | 2:2 | ||||
| 7. Jornada | 19.02.2022 | CF América [Sub 16] | - | Club Necaxa [Sub 16] | 3:2 | ||||
| 8. Jornada | 26.02.2022 | Club Necaxa [Sub 16] | - | Gallos Blancos [Sub 16] | 2:0 | ||||
| 9. Jornada | 05.03.2022 | Pumas UNAM [Sub 16] | - | Club Necaxa [Sub 16] | 1:1 | ||||
| 13. Jornada | 03.04.2022 | Club Necaxa [Sub 16] | - | CF América [Sub 16] | 2:1 | ||||
| 16. Jornada | 23.04.2022 | Club Necaxa [Sub 16] | - | FC Juárez [Sub 16] | 5:0 |  |
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| 17. Jornada | 30.04.2022 | Club Necaxa [Sub 16] | - | Pumas UNAM [Sub 16] | 2:1 | ||||
| 18. Jornada | 07.05.2022 | Cruz Azul [Sub 16] | - | Club Necaxa [Sub 16] | 2:4 |
México