| 2. Jornada | 22.02.2022 | Deportes Temuco | - | Santiago Wanderers | 1:0 | ||||
| 5. Jornada | 17.03.2022 | Santiago Wanderers | - | Rangers | 1:3 | ||||
| 12. Jornada | 01.05.2022 | Recoleta | - | Santiago Wanderers | 1:2 | ||||
| 13. Jornada | 07.05.2022 | Santiago Wanderers | - | Barnechea | 1:3 | ||||
| 14. Jornada | 13.05.2022 | Cobreloa | - | Santiago Wanderers | 1:1 | ||||
| 15. Jornada | 17.05.2022 | Santiago Wanderers | - | Universidad de Concepción | 0:0 | ||||
| 28. Jornada | 10.09.2022 | Unión San Felipe | - | Santiago Wanderers | 2:3 | ||||
| 29. Jornada | 25.09.2022 | Santiago Wanderers | - | Recoleta | 0:0 | ||||
| 34. Jornada | 02.11.2022 | Santiago Wanderers | - | Santa Cruz | 2:0 |
Brasil