| 1. Jornada | 16.04.2022 | Manta FC [Sub 19] | - | Atlético Santo Domingo [Sub 19] | 0:1 | ||||
| 2. Jornada | 29.04.2022 | Emelec [Sub 19] | - | Manta FC [Sub 19] | 1:1 | ||||
| 3. Jornada | 06.05.2022 | Manta FC [Sub 19] | - | 9 de Octubre [Sub 19] | 0:1 | ||||
| 4. Jornada | 14.05.2022 | Guayaquil City [Sub 19] | - | Manta FC [Sub 19] | 1:2 | ||||
| 5. Jornada | 27.05.2022 | Manta FC [Sub 19] | - | Delfín SC [Sub 19] | 1:0 | ||||
| 6. Jornada | 04.06.2022 | Atlético Santo Domingo [Sub 19] | - | Manta FC [Sub 19] | 3:1 | ||||
| 7. Jornada | 09.07.2022 | Manta FC [Sub 19] | - | Emelec [Sub 19] | 1:6 | ||||
| 8. Jornada | 15.07.2022 | 9 de Octubre [Sub 19] | - | Manta FC [Sub 19] | 1:3 |  |
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| 9. Jornada | 30.07.2022 | Manta FC [Sub 19] | - | Guayaquil City [Sub 19] | 0:3 | ||||
| 10. Jornada | 05.08.2022 | Delfín SC [Sub 19] | - | Manta FC [Sub 19] | 0:1 |  |
Ecuador