| 1. Jornada | 21.08.2021 | USV Eschen/Mauren | - | FC Uzwil | 4:0 | ||||
| 4. Jornada | 11.09.2021 | FC Uzwil | - | FC Baden | 1:2 | ||||
| 6. Jornada | 25.09.2021 | FC Uzwil | - | FC Paradiso | 1:1 | ||||
| 7. Jornada | 02.10.2021 | FC Freienbach | - | FC Uzwil | 2:2 |  |
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| 9. Jornada | 24.10.2021 | FC Winterthur II | - | FC Uzwil | 1:3 | ||||
| 12. Jornada | 13.11.2021 | FC Tuggen | - | FC Uzwil | 3:1 | ||||
| 14. Jornada | 27.11.2021 | FC Uzwil | - | USV Eschen/Mauren | 2:2 | ||||
| 20. Jornada | 09.04.2022 | FC Uzwil | - | FC Freienbach | 0:1 | ||||
| 18. Jornada | 13.04.2022 | FC Uzwil | - | FC Wettswil-Bonstetten | 0:2 | ||||
| 25. Jornada | 21.05.2022 | FC Uzwil | - | FC Tuggen | 1:2 | ||||
| 26. Jornada | 28.05.2022 | FC Linth 04 | - | FC Uzwil | 3:1 | |
Suiza