| 1. Jornada | 24.07.2021 | Grenoble Foot 38 | - | Paris FC | 0:4 | ||||
| 2. Jornada | 02.08.2021 | AJ Auxerre | - | Grenoble Foot 38 | 3:0 | ||||
| 3. Jornada | 07.08.2021 | Grenoble Foot 38 | - | Guingamp | 0:0 | ||||
| 5. Jornada | 21.08.2021 | Grenoble Foot 38 | - | US Quevilly-Rouen | 2:0 | ||||
| 12. Jornada | 16.10.2021 | Bastia | - | Grenoble Foot 38 | 0:0 | ||||
| 18. Jornada | 11.12.2021 | Amiens SC | - | Grenoble Foot 38 | 4:1 |
Suiza