| 1. Jornada | 04.03.2018 | San Jose Earthquakes | - | Minnesota United FC | 3:2 | ||||
| 1. Jornada | 18.03.2018 | Sporting Kansas City | - | San Jose Earthquakes | 3:2 |  |
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| 2. Jornada | 01.04.2018 | San Jose Earthquakes | - | New York City FC | 1:2 |  |
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| 2. Jornada | 08.04.2018 | Philadelphia Union | - | San Jose Earthquakes | 1:1 | |
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| 2. Jornada | 15.04.2018 | San Jose Earthquakes | - | Houston Dynamo | 2:2 | ||||
| 2. Jornada | 22.04.2018 | Orlando City | - | San Jose Earthquakes | 3:2 | |
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| 2. Jornada | 29.04.2018 | Columbus Crew | - | San Jose Earthquakes | 2:1 | ||||
| 4. Jornada | 03.06.2018 | Chicago Fire | - | San Jose Earthquakes | 2:1 | ||||
| 4. Jornada | 10.06.2018 | San Jose Earthquakes | - | Los Angeles FC | 3:4 | ||||
| 4. Jornada | 14.06.2018 | San Jose Earthquakes | - | New England Revolution | 2:2 | ||||
| 4. Jornada | 24.06.2018 | Real Salt Lake | - | San Jose Earthquakes | 1:1 | ||||
| 5. Jornada | 01.07.2018 | San Jose Earthquakes | - | Los Angeles Galaxy | 3:3 | ||||
| 8. Jornada | 28.10.2018 | Seattle Sounders | - | San Jose Earthquakes | 2:1 |
Uruguay