| 1. Jornada | 24.07.2021 | NK Veres | - | Kolos Kovalivka | 0:0 | ||||
| 2. Jornada | 30.07.2021 | Kolos Kovalivka | - | Metalist 1925 Kharkiv | 1:0 | ||||
| 4. Jornada | 15.08.2021 | Kolos Kovalivka | - | Rukh Lviv | 1:1 | ||||
| 6. Jornada | 28.08.2021 | Dinamo Kiev | - | Kolos Kovalivka | 7:0 | ||||
| 8. Jornada | 18.09.2021 | Inhulets Petrove | - | Kolos Kovalivka | 0:2 | ||||
| 9. Jornada | 24.09.2021 | Kolos Kovalivka | - | Vorskla Poltava | 0:1 | ||||
| 10. Jornada | 02.10.2021 | Kolos Kovalivka | - | Chernomorets Odessa | 2:1 | ||||
| 11. Jornada | 16.10.2021 | SK Dnipro-1 | - | Kolos Kovalivka | 2:0 | ||||
| 14. Jornada | 07.11.2021 | Kolos Kovalivka | - | Shakhtar Donetsk | 1:3 | ||||
| 15. Jornada | 21.11.2021 | Desna Chernigov | - | Kolos Kovalivka | 0:1 |  |
|||
| 3. Jornada | 24.11.2021 | FC Mynai | - | Kolos Kovalivka | 1:1 | |
|||
| 17. Jornada | 04.12.2021 | Metalist 1925 Kharkiv | - | Kolos Kovalivka | 0:1 |
Ucrania