| 1. Jornada | 14.03.2021 | BATE Borisov | - | FK Slutsk | 3:0 | ||||
| 2. Jornada | 21.03.2021 | FK Slutsk | - | Neman Grodno | 1:1 | ||||
| 3. Jornada | 04.04.2021 | Dinamo Minsk | - | FK Slutsk | 1:0 | ||||
| 6. Jornada | 23.04.2021 | FK Slaviya Mozyr | - | FK Slutsk | 3:1 | ||||
| 9. Jornada | 16.05.2021 | FK Slutsk | - | FK Minsk | 2:2 | ||||
| 13. Jornada | 18.06.2021 | FK Slutsk | - | Shakhter Soligorsk | 1:4 | ||||
| 14. Jornada | 27.06.2021 | Rukh Brest | - | FK Slutsk | 1:0 | ||||
| 15. Jornada | 03.07.2021 | FK Slutsk | - | Sputnik Rechytsa | 3:2 |  |
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| 16. Jornada | 16.07.2021 | FK Slutsk | - | BATE Borisov | 3:4 | ||||
| 17. Jornada | 24.07.2021 | Neman Grodno | - | FK Slutsk | 1:0 | ||||
| 20. Jornada | 20.08.2021 | FK Slutsk | - | FK Vitebsk | 1:2 | |
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| 21. Jornada | 29.08.2021 | FK Slutsk | - | FK Slaviya Mozyr | 2:1 | ||||
| 22. Jornada | 11.09.2021 | Dinamo Brest | - | FK Slutsk | 0:0 | ||||
| 23. Jornada | 18.09.2021 | FK Slutsk | - | FK Gomel | 1:4 | ||||
| 24. Jornada | 25.09.2021 | FK Minsk | - | FK Slutsk | 2:1 | ||||
| 25. Jornada | 03.10.2021 | FK Slutsk | - | Energetik-BGU Minsk | 2:0 | ||||
| 26. Jornada | 16.10.2021 | FK Isloch Minsk | - | FK Slutsk | 2:0 |
Rusia